Nature serves as a profound source of inspiration for every individual on our planet. Living organisms produce molecules essential for their survival, and chemists play a crucial role in isolating and identifying these compounds, exploring their structures, and uncovering their applications in diverse biological activities. Natural products, in particular, play a pivotal role in drug discovery, a significant portion of existing drugs either originate from natural sources or are synthetic analogs of natural compounds. Given the limited availability of these small molecules in nature, synthesizing them in the laboratory becomes imperative to meet research and medical needs. The total synthesis of these molecules involves multiple synthetic modifications of commercially available starting materials. Particularly, natural products with multiple asymmetric stereogenic centers demand a profound understanding of chemical knowledge to achieve their laboratory synthesis in enantiomerically pure form.

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Our team is primarily dedicated to the total synthesis or multi-step synthesis of complex natural products, addressing their structural challenges. Additionally, we actively contribute to the development of new synthetic methods and the design of novel catalysts and chiral auxiliaries for various synthetic applications. Through these endeavors, we aim to advance the understanding and application of organic chemistry in the pursuit of addressing critical challenges in drug discovery and synthesis.